1-alfa-hydroxylasa 25-hydroxyvitaminu D3 - D08.244.453.915.400

Mitochondriální cytochrom P450 enzym, který katalyzuje 1-alfa-hydroxylace 25-hydroxyvitaminu D3 (také známý jako 25-hydroxycholekalciferolu) v přítomnosti molekulárního kyslíku a NADPH-FERRIHEMOPROTEIN reduktázy. Tento enzym, kódovaný genem CYP27B1, převede 25-hydroxyvitamin D3 1-alpha ,25-dihydroxyvitamin D3, který je aktivní forma vitaminu D v regulaci růstu kostí a metabolismus vápníku. Tento enzym je aktivní také na rostlinnou 25-hydroxyvitaminu D2 (Ergocalciferol).

Kód deskriptoru: D08.244.453.915.400

Chemikálie a léčiva
D08.244 - cytochromy
D08.244.453.915 - steroidhydroxylasy
D08.244.453.915.050 - synthasa aldosteronu
D08.244.453.915.099 - aromatasa
D08.244.453.915.149 - cytochrom P-450 CYP27A1
D08.244.453.915.200 - cholesterol-7-alfa-hydroxylasa
D08.244.453.915.400 - 1-alfa-hydroxylasa 25-hydroxyvitaminu D3
D08.244.453.915.730 - steroid-12-alfa-hydroxylasa
D08.244.453.915.737 - steroid-16-alfa-hydroxylasa
D08.244.453.915.748 - steroid-17-alfa-hydroxylasa
D08.244.453.915.750 - steroid-11-beta-hydroxylasa
D08.244.453.915.760 - steroid-21-hydroxylasa
D08.244.453.915.880 - sterol-14-demethylasa
D08.811 - enzymy
D08.811.682 - oxidoreduktázy
D08.811.682.690 - oxygenasy
D08.811.682.690.708 - oxygenasy se smíšenou funkcí
D08.811.682.690.708.170 - systém (enzymů) cytochromů P-450
D08.811.682.690.708.170.915 - steroidhydroxylasy
D08.811.682.690.708.170.915.050 - synthasa aldosteronu
D08.811.682.690.708.170.915.099 - aromatasa
D08.811.682.690.708.170.915.150 - cytochrom P-450 CYP27A1
D08.811.682.690.708.170.915.200 - cholesterol-7-alfa-hydroxylasa
D08.811.682.690.708.170.915.212 - enzymštěpící postranní řetězce cholesterolu
D08.811.682.690.708.170.915.400 - 1-alfa-hydroxylasa 25-hydroxyvitaminu D3
D08.811.682.690.708.170.915.730 - steroid-12-alfa-hydroxylasa
D08.811.682.690.708.170.915.737 - steroid-16-alfa-hydroxylasa
D08.811.682.690.708.170.915.748 - steroid-17-alfa-hydroxylasa
D08.811.682.690.708.170.915.750 - steroid-11-beta-hydroxylasa
D08.811.682.690.708.170.915.760 - steroid-21-hydroxylasa
D08.811.682.690.708.170.915.880 - sterol-14-demethylasa
D08.811.682.690.708.783 - steroidhydroxylasy
D08.811.682.690.708.783.050 - synthasa aldosteronu
D08.811.682.690.708.783.099 - aromatasa
D08.811.682.690.708.783.150 - cytochrom P-450 CYP27A1
D08.811.682.690.708.783.200 - cholesterol-7-alfa-hydroxylasa
D08.811.682.690.708.783.400 - 1-alfa-hydroxylasa 25-hydroxyvitaminu D3
D08.811.682.690.708.783.730 - steroid-12-alfa-hydroxylasa
D08.811.682.690.708.783.737 - steroid-16-alfa-hydroxylasa
D08.811.682.690.708.783.745 - steroid-17-alfa-hydroxylasa
D08.811.682.690.708.783.750 - steroid-11-beta-hydroxylasa
D08.811.682.690.708.783.760 - steroid-21-hydroxylasa
D08.811.682.690.708.783.880 - sterol-14-demethylasa
D12.776 - proteiny
D12.776.422 - hemeproteiny
D12.776.422.220 - cytochromy
D12.776.422.220.453.915 - steroidhydroxylasy
D12.776.422.220.453.915.050 - synthasa aldosteronu
D12.776.422.220.453.915.099 - aromatasa
D12.776.422.220.453.915.150 - cytochrom P-450 CYP27A1
D12.776.422.220.453.915.200 - cholesterol-7-alfa-hydroxylasa
D12.776.422.220.453.915.400 - 1-alfa-hydroxylasa 25-hydroxyvitaminu D3
D12.776.422.220.453.915.730 - steroid-12-alfa-hydroxylasa
D12.776.422.220.453.915.737 - steroid-16-alfa-hydroxylasa
D12.776.422.220.453.915.748 - steroid-17-alfa-hydroxylasa
D12.776.422.220.453.915.750 - steroid-11-beta-hydroxylasa
D12.776.422.220.453.915.760 - steroid-21-hydroxylasa
D12.776.422.220.453.915.880 - sterol-14-demethylasa

Zpět na MeSH strom


Autorská práva pro českou verzi tezauru Medical Subject Headings patří Národní lékařské knihovně.