Lovastatin - D02.455.426.559.847.638.400

Houbové metabolit izolován z kultur Aspergillus terreus. Sloučenina je silným anticholesteremic agent. Inhibuje 3-hydroxy-3-methylglutaryl koenzymu A reduktázy (hydroxymethylglutaryl COA reduktázy), což je rychlost omezující enzym v biosyntéze cholesterolu. To také stimuluje produkci lipoproteinu o nízké hustotě receptorů v játrech.

Kód deskriptoru: D02.455.426.559.847.638.400

Chemikálie a léčiva
D02.455 - uhlovodíky
D02.455.426 - uhlovodíky cyklické
D02.455.426.559 - uhlovodíky aromatické
D02.455.426.559.847.638 - naftaleny
D02.455.426.559.847.638.059 - acenafteny
D02.455.426.559.847.638.120 - bunaftin
D02.455.426.559.847.638.162 - sevin
D02.455.426.559.847.638.204 - dimethylaminonaftalensulfonylové sloučeniny
D02.455.426.559.847.638.400 - lovastatin
D02.455.426.559.847.638.400.900 - simvastatin
D02.455.426.559.847.638.472 - kyseliny naftalenoctové
D02.455.426.559.847.638.555 - naftalensulfonany
D02.455.426.559.847.638.638 - naftoly
D02.455.426.559.847.638.721 - naftochinony
D02.455.426.559.847.638.845 - 1-naftylamin
D02.455.426.559.847.638.850 - 2-naftylamin
D02.455.426.559.847.638.870 - 1-naftylisothiokyanát
D02.455.426.559.847.638.900 - naftylvinylpyridin
D02.455.426.559.847.638.930 - pravastatin
D02.455.426.559.847.638.945 - propranolol
D02.455.426.559.847.638.960 - tetrahydronaftaleny
D02.455.426.559.847.638.975 - tolnaftát
D04.615.638 - naftaleny
D04.615.638.059 - acenafteny
D04.615.638.120 - bunaftin
D04.615.638.162 - sevin
D04.615.638.400 - lovastatin
D04.615.638.400.900 - simvastatin
D04.615.638.472 - kyseliny naftalenoctové
D04.615.638.555 - naftalensulfonany
D04.615.638.596 - naftalimidy
D04.615.638.638 - naftoly
D04.615.638.721 - naftochinony
D04.615.638.845 - 1-naftylamin
D04.615.638.850 - 2-naftylamin
D04.615.638.870 - 1-naftylisothiokyanát
D04.615.638.900 - naftylvinylpyridin
D04.615.638.930 - pravastatin
D04.615.638.945 - propranolol
D04.615.638.960 - tetrahydronaftaleny
D04.615.638.975 - tolnaftát

Zpět na MeSH strom


Autorská práva pro českou verzi tezauru Medical Subject Headings patří Národní lékařské knihovně.